anticorps bA42B19.1, anticorps typ, anticorps Ptpn20, anticorps protein tyrosine phosphatase, non-receptor type 20, anticorps PTPN20, anticorps Ptpn20
Sujet
The product of the PTPN20A (and PTPN20B) gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes and several are mutated in human diseases. Chromosome 10q contains a segmental duplication resulting in multiple copies of the protein tyrosine phosphatase, non-receptor type 20 gene. The two nearly identical copies are designated as PTPN20A and PTPN20B. A third copy is only partially duplicated and contains a pseudogene, designated as PTPN20C. This gene encodes the more telomeric copy, PTPN20B. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.Synonyms: PTPN20A, PTPN20B, RP11-142I17.1, Tyrosine-protein phosphatase non-receptor type 20