Importin 11 anticorps (C-Term)
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- Antigène Voir toutes Importin 11 (IPO11) Anticorps
- Importin 11 (IPO11)
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Épitope
- AA 906-970, C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Importin 11 est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody recognizes Human RanBP11 / Importin-11 (C-term).
- Purification
- Protein A column, followed by peptide affinity purification
- Immunogène
- KLH conjugated synthetic peptide between 906~970 amino acids from the C-terminal region of Human RanBP11 / Importin-11 Genename: IPO11
- Isotype
- Ig Fraction
- Top Product
- Discover our top product IPO11 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- Importin 11 (IPO11)
- Autre désignation
- RanBP11 / Importin-11 (IPO11 Produits)
- Synonymes
- anticorps MGC83107, anticorps IPO11, anticorps slrn, anticorps ranbp11, anticorps RanBP11, anticorps 1700081H05Rik, anticorps 2510001A17Rik, anticorps AI314624, anticorps AW555235, anticorps E330021B14Rik, anticorps Ranbp11, anticorps importin 11 S homeolog, anticorps importin 11, anticorps importin-11, anticorps ipo11.S, anticorps ipo11, anticorps IPO11, anticorps AFUA_1G03590, anticorps BDBG_04626, anticorps LOC100162908, anticorps Ipo11
- Sujet
- IPO11 functions in nuclear protein import as nuclear transport receptor. It serves as receptor for nuclear localization signals (NLS) in cargo substrates and is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). It mediates the nuclear import of UBE2E3, and of RPL12 (By similarity).Synonyms: IPO11, Imp11, Ran-binding protein 11
- Poids moléculaire
- 112535 Da
- ID gène
- 51194
- NCBI Accession
- NP_001128251
- Pathways
- Protein targeting to Nucleus
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