anticorps tloc1, anticorps TLOC1, anticorps wu:fb57b06, anticorps zgc:114073, anticorps Dtrp1, anticorps HTP1, anticorps TP-1, anticorps 3100002M17Rik, anticorps AI844545, anticorps AW545092, anticorps Tloc1, anticorps Ab2-292, anticorps SEC62 homolog, preprotein translocation factor S homeolog, anticorps SEC62 homolog, preprotein translocation factor, anticorps membrane unit of ER protein translocation apparatus, anticorps SEC62 homolog (S. cerevisiae), anticorps sec62.S, anticorps SEC62, anticorps sec62, anticorps Sec62
Sujet
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.Synonyms: Translocation protein 1, Translocation protein SEC62