SNX13 anticorps (C-Term)

N° du produit ABIN954885

Détail du produit anti-SNX13 anticorps

Antigène: SNX13 (Sorting Nexin 13 (SNX13))

Épitope: AA 779-807, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNX13 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects human SNX13 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Purified through a protein A column; followed by peptide affinity purification.

Immunogène: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 779-807aa) of human Sorting nexin-13 (SNX13).

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SNX13

Antigène: SNX13 (Sorting Nexin 13 (SNX13))

Autre désignation: Sorting Nexin-13 (SNX13) (SNX13 Produits)

Synonymes: anticorps MGC142644, anticorps DKFZp469H181, anticorps Rgs-px1, anticorps mKIAA0713, anticorps RGS-PX1, anticorps sorting nexin 13, anticorps SNX13, anticorps Snx13

Sujet: SNX13 gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.Synonyms: KIAA0713, RGS domain- and PHOX domain-containing protein

ID gène: 23161

NCBI Accession: NP_055947

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling