SPACA1 anticorps (N-Term)

N° du produit ABIN954901

Détail du produit anti-SPACA1 anticorps

Antigène: SPACA1 (Sperm Acrosome Associated 1 (SPACA1))

Épitope: AA 49-78, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPACA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: Recognizes SACA1 (N-term).

Purification: Protein A column followed by peptide Affinity purification

Immunogène: KLH conjugated synthetic peptide between 49-78 amino acids from the N-terminal region of Human SACA1 Genename: SPACA1

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SPACA1

Antigène: SPACA1 (Sperm Acrosome Associated 1 (SPACA1))

Autre désignation: SPACA1 / SAMP32 (SPACA1 Produits)

Synonymes: anticorps SAMP32, anticorps 1700124L11Rik, anticorps 4930540L03Rik, anticorps sperm acrosome associated 1, anticorps SPACA1, anticorps Spaca1

Sujet: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.Synonyms: Sperm acrosomal membrane-associated protein 32, Sperm acrosome membrane-associated protein 1

ID gène: 81833

NCBI Accession: NP_112222