anticorps SITAC, anticorps SITAC18, anticorps ST-2, anticorps syndecan binding protein 2, anticorps syndecan binding protein (syntenin) 2, anticorps suppression of tumorigenicity 2, anticorps SDCBP2, anticorps Sdcbp2, anticorps ST2
Sujet
Syntenin 2 binds to the cytoplasmic domains of the syndecans: it contains a tandem repeat of PDZ domains that reacts with the FYA (phe-tyr-ala) C-terminal amino acid sequence of the syndecans. Cells that overexpress the fusion protein show numerous cell surface extensions, suggesting that Syntenin 2 may have an effect on cytoskeleton-membrane organization. Therefore, Syntenin 2 may function as an adaptor that couples syndecans to cytoskeletal proteins or cytosolic downstream signal-effectors.Synonyms: SITAC18, Syndecan-binding protein 2