XDH anticorps (N-Term)

N° du produit ABIN955594

Détail du produit anti-XDH anticorps

Antigène: XDH (Xanthine Dehydrogenase (XDH))

Épitope: AA 213-242, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XDH est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects Xanthine dehydrogenase/oxidase (N-term).

Réactivité croisée (Details): Species reactivity (tested):Human, mouse.

Purification: Protein A column followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 213~242 amino acids from the N-terminal region of human XDH

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-XDH (ABIN955594)

Ross, Katzov-Eckert, Dubé, Brooks, Rassekh, Barhdadi, Feroz-Zada, Visscher, Brown, Rieder, Rogers, Phillips, Carleton, Hayden: "Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy." dans: Nature genetics, Vol. 41, Issue 12, pp. 1345-9, (2009) (PubMed).

Détails sur XDH

Antigène: XDH (Xanthine Dehydrogenase (XDH))

Autre désignation: XDH (XDH Produits)

Synonymes: anticorps XO, anticorps XOR, anticorps Xor, anticorps Xox-1, anticorps Xox1, anticorps XDH, anticorps im:7146167, anticorps DDBDRAFT_0219626, anticorps DDBDRAFT_0230176, anticorps DDB_0219626, anticorps DDB_0230176, anticorps xanthine dehydrogenase, anticorps xanthine dehydrogenase/oxidase, anticorps Xanthine dehydrogenase, anticorps XDH, anticorps Xdh, anticorps xdh, anticorps LOC576712, anticorps Trebr_1754

Sujet: XDH belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. This protein can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.Synonyms: Xanthine dehydrogenase/oxidase

ID gène: 7498

NCBI Accession: NP_000370

Pathways: Positive Regulation of Endopeptidase Activity