MANF anticorps

N° du produit ABIN956418

Détail du produit anti-MANF anticorps

Antigène: MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MANF est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Human MANF

Purification: IgG fraction purifiedwith Protein G affinity chromatorgaphy

Immunogène: Recombinant human MANF protein produced using CHO-basedIcosagen Cell factory Ltd. proprietary suspension cell line. Immunogen is purifiedfrom cell culture supernatant

Clone: 1G12

Isotype: IgG1

Information d'application

Indications d'application: ELISA1:32 000, Western immunoblotting 1:2000 – 1:4000. Monoclonal antibody working titer has to be established practically for each particular antigen and assay format

Commentaires:

Synonym: ARMET, ARP

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml

Buffer: PBS pH 7.4, with 0.1%

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Divide antibody into aliquots prior usage. Avoid multiple freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: This product is shipped in non-frozen liquid form in ambient conditions

Détails sur MANF

Antigène: MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))

Autre désignation: MANF (MANF Produits)

Synonymes: anticorps ARMET, anticorps ARP, anticorps 3230402M22Rik, anticorps AA407711, anticorps AA408789, anticorps AA673178, anticorps Armet, anticorps D17914, anticorps D18Mgi17, anticorps MANF, anticorps RBM15B, anticorps ARP-like, anticorps CG7013, anticorps DmMANF, anticorps Dmel\\CG7013, anticorps anon-EST:ParkEST188, anticorps arp, anticorps armet, anticorps im:6909481, anticorps zgc:153327, anticorps manf, anticorps mesencephalic astrocyte derived neurotrophic factor, anticorps mesencephalic astrocyte-derived neurotrophic factor, anticorps RNA binding motif protein 15B, anticorps Mesencephalic astrocyte-derived neurotrophic factor, anticorps mesencephalic astrocyte-derived neurotrophic factor S homeolog, anticorps MANF, anticorps Manf, anticorps RBM15B, anticorps manf, anticorps manf.S

Sujet: MANF is a trophic factor for midbrain dopamine neuronsin vivo. It prevents the 6-OHDA-induced degeneration of dopamine neurons in rodent models of Parkinson’sdisease (Lindholm et al., 2008, Voutilainen et al., 2009). When administeredafter 6-OHDA-lesioning it restores the dopaminergic function and prevents degenerationof dopamine neurons in substantia nigra pars compacta

UniProt: P55145