CCL20 anticorps
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- Antigène Voir toutes CCL20 Anticorps
- CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CCL20 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Neutralization (Neut), Radioimmunoassay (RIA)
- Specificité
- This Protein A purified antibody was heated to 56°C for 30 minutes. In ELISA and other immunoreactive assays, this antibody will recognize both native and recombinant human MIP-3alpha in cell supernatants and certain body fluids. A control of similarly diluted normal rabbit IgG is recommended.
- Attributs du produit
- MIP-3alpha (also known as C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1) is a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. MIP-3alpha inhibits proliferation of myeloid progenitors in colony formation assays and may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. MIP-3alpha also possesses antibacterial activity against E.coli and S.aureus. MIP-3alpha is a secreted protein that is expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of expression are also seen in thymus, prostate, testis, small intestine and colon. C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
- Purification
- purified
- Immunogène
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This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant human MIP-3alpha protein.
Immunogen Type: RecombinantProtein - Isotype
- IgG
- Top Product
- Discover our top product CCL20 Anticorps primaire
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- Indications d'application
- This purified antibody has been tested for use in ELISA and western blotting. Reactivity is also expected in neutralizations, radioimmunoassay and immunohistochemistry. The endotoxin content is estimated to be <10 pg/µl by the LAL method. By western blot a band approximately 11 kDa in size corresponding to native human MIP-3α protein is expected in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.
- Commentaires
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Gene Name: CCL20
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
- Concentration
- 1.0 mg/mL
- Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Agent conservateur
- Without preservative
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
- Date de péremption
- 12 months
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- Antigène
- CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))
- Autre désignation
- MIP-3 alpha (CCL20 Produits)
- Synonymes
- anticorps MIP-3ALPHA, anticorps CCL20, anticorps si:dkey-150o13.1, anticorps CKb4, anticorps LARC, anticorps MIP-3-alpha, anticorps MIP-3a, anticorps MIP3A, anticorps SCYA20, anticorps ST38, anticorps MIP-3A, anticorps MIP-3[a], anticorps Scya20, anticorps exodus-1, anticorps C-C motif chemokine ligand 20, anticorps chemokine (C-C motif) ligand 20b, anticorps chemokine (C-C motif) ligand 20, anticorps CCL20, anticorps ccl20b, anticorps Ccl20
- Sujet
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MIP-3α (also known as C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1) is a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. MIP-3α inhibits proliferation of myeloid progenitors in colony formation assays and may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. MIP-3α also possesses antibacterial activity against E.coli and S.aureus. MIP-3α is a secreted protein that is expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of expression are also seen in thymus, prostate, testis, small intestine and colon. C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
Synonyms: MIP-3α , CCL20, C-C motif chemokine 20, small-inducible cytokine A20, macrophage inflammatory protein 3 alpha, MIP-3-alpha, liver and activation-regulated chemokine, CC chemokine LARC and beta chemokine exodus-1 - ID gène
- 6364, 4759076
- UniProt
- P78556
- Pathways
- Phosphorylation & l'infection par le SRAS-CoV-2
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