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AKT3 anticorps
AKT3
Reactivité: Humain
WB, ELISA
Monoclonal
unconjugated
Détail du produit anti-AKT3 anticorps
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Antigène
Voir toutes AKT3 Anticorps
AKT3
(V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3))
Reactivité
Toutes les réactivités sur AKT3 Anticorps
Humain
Hôte
Veuillez nous consulter SVP
Clonalité
Toutes les clonalités sur AKT3 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers AKT3 Anticorps
Cet anticorp AKT3 est non-conjugé
Application
Tous les applications à travers AKT3 Anticorps.
Western Blotting (WB), ELISA
Specificité
Ni-NTA purified truncated recombinant Akt3 expressed in E. Coli strain BL21 (DE3)
Purification
Crude ascites.
Top Product
Discover our top product AKT3 Anticorps primaire
Alternatives
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Information d'application
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Indications d'application
Western Blot: 1: 500- 1: 2000 ELISA: Propose dilution 1: 10,000. Determining optimal working dilutions by titration test.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Stock
-20 °C
Références pour anticorps anti-AKT3 (ABIN965532)
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Easton, Cho, Roovers, Shineman, Mizrahi, Forman, Lee, Szabolcs, de Jong, Oltersdorf, Ludwig, Efstratiadis, Birnbaum : "Role for Akt3/protein kinase Bgamma in attainment of normal brain size. " dans: Molecular and cellular biology , Vol. 25 , Issue 5 , pp. 1869-78 , (2005 ) (PubMed ).
Stahl, Sharma, Cheung, Zimmerman, Cheng, Bosenberg, Kester, Sandirasegarane, Robertson : "Deregulated Akt3 activity promotes development of malignant melanoma. " dans: Cancer research , Vol. 64 , Issue 19 , pp. 7002-10 , (2004 ) (PubMed ).
Détails sur AKT3
(cache)
Antigène
AKT3
(V-Akt Murine Thymoma Viral Oncogene Homolog 3 (Protein Kinase B, Gamma) (AKT3))
Autre désignation
Akt3 (AKT3 Produits )
Synonymes
anticorps MPPH, anticorps PKB-GAMMA, anticorps PKBG, anticorps PRKBG, anticorps RAC-PK-gamma, anticorps RAC-gamma, anticorps STK-2, anticorps AI851531, anticorps D930002M15Rik, anticorps Nmf350, anticorps Pkbg, anticorps AKT serine/threonine kinase 3, anticorps thymoma viral proto-oncogene 3, anticorps v-akt murine thymoma viral oncogene homolog 3b, anticorps AKT3, anticorps Akt3, anticorps akt3b
Sujet
Akt3 (also designated protein kinase B gamma or vakt murine thymoma viral oncogene homolog 3),with 479-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt2. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake.Akt3 is not required for the maintenance of normal carbohydrate metabolism but is essential for the attainment of normal organ size. Identifying Akt3 as a selective target in melanoma cells also provides new therapeutic opportunities for patients in the advanced stages of this disease.
ID gène
10000
Pathways
Signalisation PI3K-Akt , Signalisation RTK , Signalisation TLR , Hepatitis C , VEGF Signaling
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