Purified by antigen-specific affinity chromatography.
Immunogène
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of mouse ALDH1L1(Aldehyde dehydrogenase 1 family member L1)
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Krupenko, Wagner: "Aspartate 142 is involved in both hydrolase and dehydrogenase catalytic centers of 10-formyltetrahydrofolate dehydrogenase." dans: The Journal of biological chemistry, Vol. 274, Issue 50, pp. 35777-84, (2000) (PubMed).
Case, Kaisaki, Steele: "Resolution of rat liver 10-formyltetrahydrofolate dehydrogenase/hydrolase activities." dans: The Journal of biological chemistry, Vol. 263, Issue 21, pp. 10204-7, (1988) (PubMed).
Antigène
ALDH1L1
(Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1))
anticorps 10-FTHFDH, anticorps 10-fTHF, anticorps FDH, anticorps FTHFD, anticorps Fthfd, anticorps 1810048F20Rik, anticorps Neut2, anticorps fthfd, anticorps ALDH1L1, anticorps DKFZp469C068, anticorps aldehyde dehydrogenase 1 family member L1, anticorps aldehyde dehydrogenase 1 family, member L1, anticorps cytosolic 10-formyltetrahydrofolate dehydrogenase, anticorps aldehyde dehydrogenase 1 family member L1 L homeolog, anticorps ALDH1L1, anticorps Aldh1l1, anticorps aldh1l1, anticorps LOC476506, anticorps LOC100465263, anticorps aldh1l1.L
Sujet
ALDH1L1 ((Aldehyde dehydrogenase 1 family member L1) converts 10-formyltetrahydrofolate, a precursor for nucleotide biosynthesis, to tetrahydrofolate. The protein comprises two functional domains: a hydrolase domain that removes a formyl group from 10-formyltetrahydrofolate and a NADP(+)-dependent dehydrogenase domain that reduces the formyl to carbon dioxide. It is localized in cytoplasm and contains 1 acyl carrier domain. In the N-terminal section, it belongs to the GART family. In the C-terminal section, it belongs to the aldehyde dehydrogenase family.