APOA5 anticorps

N° du produit ABIN7446174

Détail du produit anti-APOA5 anticorps

Antigène: APOA5 (Apolipoprotein A-V (APOA5))

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Monoclonal

Conjugué: Cet anticorp APOA5 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Ni-NTA purified recombinant human Apoa5 expressed in E. Coli strain BL21 (DE3).

Purification: Antibodies are purified by protein G affinity chromatography.

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: Dilution 1: 1,000- 1: 2,000
Suggested ELISA dilution 1: 4,000
ptimized dilution must be determined by end user.

Restrictions: For Research Use only

Stockage

Stock: -20 °C

Détails sur APOA5

Antigène: APOA5 (Apolipoprotein A-V (APOA5))

Autre désignation: APOA5 (APOA5 Produits)

Synonymes: anticorps APOAV, anticorps RAP3, anticorps 1300007O05Rik, anticorps Apoav, anticorps apo-AV, anticorps apoA-V, anticorps APOA5, anticorps MGC140487, anticorps rap3, anticorps apoav, anticorps apoa-v, anticorps apolipoprotein A5, anticorps apolipoprotein A-V, anticorps apolipoprotein A5 L homeolog, anticorps APOA5, anticorps Apoa5, anticorps apoa5.L, anticorps apoa5

Sujet: Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50-70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Despite these compelling molecular biology data, relatively little is known about ApoA5 protein in human serum. This antibody pair detected recombinant apoa5 protein in sandwich ELISA format and could be potential reagents for the development of clinical diagnostic kits.

ID gène: 116519

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism