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BLK anticorps

Name: BLK anticorps
Brand: antibodies-online
SKU: ABIN965674
Price: 594 EUR
Availability: InStock

BLK Reactivité: Humain WB, ELISA, IHC Monoclonal unconjugated

(1 reference)

N° du produit ABIN965674

Fiche de données

Antigène Voir toutes BLK Anticorps

BLK (B Lymphoid Tyrosine Kinase (BLK))
Reactivité
66

24

15

2

1

1

1

1

1

1

1
Humain

Hôte

Veuillez nous consulter SVP
Clonalité
56

10
Monoclonal
Conjugué
35

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp BLK est non-conjugé
Application
50

37

28

13

13

8

4

3

2

2

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité

Ni-NTA purified truncated recombinant BLK expressed in E. Coli strain BL21 (DE3)

Purification

Crude ascites.

Isotype

IgG1

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BLK Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated

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BLK Reactivité: Humain ELISA, IHC Hôte: Souris Monoclonal 9D10D1 unconjugated

anti-B Lymphoid Tyrosine Kinase (BLK) (N-Term) antibody
BLK Reactivité: Humain, Souris WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated

Indications d'application

Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Restrictions

For Research Use only
Format

Liquid

Stock

-20 °C
Tretter, Ross, Dordai, Desiderio: "Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk." dans: The Journal of experimental medicine, Vol. 198, Issue 12, pp. 1863-73, (2003) (PubMed).
Antigène

BLK (B Lymphoid Tyrosine Kinase (BLK))

Autre désignation

BLK (BLK Produits)

Synonymes

anticorps bltk, anticorps si:dkey-33i22.2, anticorps zgc:136231, anticorps MODY11, anticorps BLK proto-oncogene, Src family tyrosine kinase, anticorps B lymphoid kinase, anticorps blk, anticorps BLK, anticorps Blk

Sujet

BLK ( B lymphoid tyrosine kinase), with 505-amino acid protein (about 56KDa), belongs to the Src nonreceptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.

ID gène

640

Pathways

Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling