anticorps COPT2, anticorps CTR2, anticorps hCTR2, anticorps ctr2, anticorps xem1, anticorps copt2, anticorps SLC31A2, anticorps AI604396, anticorps copper transporter 2, anticorps solute carrier family 31 member 2, anticorps solute carrier family 31 member 2 S homeolog, anticorps solute carrier family 31, member 2, anticorps copper transporter 2, anticorps SLC31A2, anticorps slc31a2.S, anticorps slc31a2, anticorps Slc31a2, anticorps COPT2
Sujet
The COPT2(copper transporter 2) is involved in low-affinity copper uptake. COPT2 is a multi-pass membrane protein and belongs to the SLC31A transporter family. The redox active metal copper is an essential cofactor in critical biological processes such as respiration, iron transport,oxidative stress protection, hormone production, and pigmentation. A widely conserved family of high-affinity copper transport proteins (Ctr proteins) mediates copper uptake at the plasma membrane. A series of clustered methionine residues in the hydrophilic extracellular domain, and an MXXXM motif in the second transmembrane domain, are important for copper uptake. These methionine probably coordinate copper during the process of metal transport