Cytokeratin 5 anticorps

N° du produit ABIN965962

Détail du produit anti-Cytokeratin 5 anticorps

Antigène: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cytokeratin 5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of Cytokeratin 5 expressed in E. Coli.

Clone: 1E1

Isotype: IgG1

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-Cytokeratin 5 (ABIN965962)

Gu, Kim, Ichiki, Park, Nagai, Kitajima: "A usual frameshift and delayed termination codon mutation in keratin 5 causes a novel type of epidermolysis bullosa simplex with migratory circinate erythema." dans: The Journal of investigative dermatology, Vol. 121, Issue 3, pp. 482-5, (2003) (PubMed).

Détails sur Cytokeratin 5

Antigène: Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))

Autre désignation: Cytokeratin 5 (KRT5 Produits)

Synonymes: anticorps 3300001P10Rik, anticorps AW146334, anticorps CK5, anticorps K5, anticorps Krt2-5, anticorps Tfip8, anticorps DDD, anticorps DDD1, anticorps EBS2, anticorps KRT5A, anticorps Sak57, anticorps ckii, anticorps wu:fb02h09, anticorps wu:fj02d02, anticorps wu:fk78b12, anticorps zfCKII, anticorps KRT75, anticorps CK-5, anticorps Keratin-5, anticorps keratin 5, anticorps Krt5, anticorps KRT5, anticorps krt5

Sujet: Cytokeratin 5, also known as CK5, KRT5. It is a member of the keratin gene family. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin5 gene (KRT5) have been shown to result in the autosomal dominant disorderepidermolysis bullosa (EB). Defects in KRT5 are a cause of epidermolysis bullosa simplex.
Synonyms: K5, CK5, KRT5A, KRT5

Poids moléculaire: 62.3kDa

ID gène: 3852