Daf-2 anticorps (C-Term)

N° du produit ABIN965970

Détail du produit anti-Daf-2 anticorps

Antigène: Daf-2 (DAF2) (Decay Accelerating Factor 2 (DAF2))

Épitope: C-Term

Reactivité: C. elegans

Hôte: Lapin

Clonalité: Polyclonal

Application: Immunohistochemistry (IHC)

Purification: Purified by antigen-specific affinity chromatography.

Immunogène: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of Caenorhabditis elegans daf-2(Abnormal dauer formation protein 2)

Information d'application

Indications d'application: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur Daf-2

Antigène: Daf-2 (DAF2) (Decay Accelerating Factor 2 (DAF2))

Autre désignation: Daf-2

Synonymes: anticorps AI323748, anticorps Cd55b, anticorps Daf, anticorps Daf-TM, anticorps TM-DAF, anticorps CD55 molecule, decay accelerating factor for complement B, anticorps Insulin-like receptor subunit beta, anticorps Cd55b, anticorps daf-2

Sujet: The daf-2 is an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. A C. elegans neurosecretory signaling system regulates whether animals enter the reproductive life cycle or arrest development at the long-lived dauer diapause stage. daf-2, a key gene in the genetic pathway that mediates this endocrine signaling, encodes an insulin receptor family member. Decreases in DAF-2 signaling induce metabolic and developmental changes, as in mammalian metabolic control by the insulin receptor. Decreased DAF-2 signaling also causes an increase in life-span. Lifespan regulation by insulin-like metabolic control is analogous to mammalian longevity enhancement induced by caloric restriction, suggesting a general link between metabolism, diapause, and longevity.