DCK anticorps (N-Term)

N° du produit ABIN965975

Détail du produit anti-DCK anticorps

Antigène: DCK (Deoxycytidine Kinase (DCK))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCK est non-conjugé

Application: Immunohistochemistry (IHC)

Purification: Purified by antigen-specific affinity chromatography.

Immunogène: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human DCK (deoxycytidine kinase)

Information d'application

Indications d'application: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-DCK (ABIN965975)

Innoceta, Galluzzi, Ruzzo, Andreoni, Chiarantini, Magnani: "Molecular basis of 2',3'-dideoxycytidine-induced drug resistance in human cells." dans: Molecular and cellular biochemistry, Vol. 231, Issue 1-2, pp. 173-7, (2002) (PubMed).

Détails sur DCK

Antigène: DCK (Deoxycytidine Kinase (DCK))

Autre désignation: DCK (DCK Produits)

Synonymes: anticorps dck, anticorps DCK, anticorps wu:fc15f06, anticorps zgc:101771, anticorps dck1, anticorps deoxycytidine kinase, anticorps deoxycytidine kinase, gene 2 L homeolog, anticorps deoxycytidine kinase, gene 2, anticorps Deoxycytidine kinase, anticorps deoxycytidine kinase, gene 1 L homeolog, anticorps DCK, anticorps dck, anticorps dck.2.L, anticorps dck.2, anticorps Dck, anticorps FPV059, anticorps FPV151, anticorps dck.1.L

Sujet: Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.