EGFR anticorps
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- Antigène Voir toutes EGFR Anticorps
- EGFR (Epidermal Growth Factor Receptor (EGFR))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EGFR est non-conjugé
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Application
- Immunohistochemistry (IHC)
- Specificité
- EGFR (Ab-1092) antibody detects endogenous levels of total EGFR protein.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogène
- The antiserum was produced against synthesized non-phosphopeptide derived from human EGFR around the phosphorylation site of tyrosine 1092 (P-E-YP-I-N).
- Top Product
- Discover our top product EGFR Anticorps primaire
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- Indications d'application
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WB: 1:500~1:1000
IHC: 1:50~1:100. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100ug/100ul.
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTP." dans: Nature cell biology, Vol. 7, Issue 1, pp. 78-85, (2005) (PubMed).
: "Differential activation of epidermal growth factor (EGF) receptor downstream signaling pathways by betacellulin and EGF." dans: Endocrinology, Vol. 145, Issue 9, pp. 4232-43, (2004) (PubMed).
: "EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 36, pp. 13306-11, (2004) (PubMed).
: "Sequence-specific peptide aptamers, interacting with the intracellular domain of the epidermal growth factor receptor, interfere with Stat3 activation and inhibit the growth of tumor cells." dans: The Journal of biological chemistry, Vol. 278, Issue 39, pp. 37610-21, (2003) (PubMed).
: "Ganglioside GM3 blocks the activation of epidermal growth factor receptor induced by integrin at specific tyrosine sites." dans: The Journal of biological chemistry, Vol. 278, Issue 49, pp. 48770-8, (2003) (PubMed).
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Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTP." dans: Nature cell biology, Vol. 7, Issue 1, pp. 78-85, (2005) (PubMed).
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- Antigène
- EGFR (Epidermal Growth Factor Receptor (EGFR))
- Autre désignation
- EGFR (EGFR Produits)
- Synonymes
- anticorps C-erb, anticorps CG10079, anticorps D-EGFR, anticorps D-Egf, anticorps DEGFR, anticorps DER, anticorps DER flb, anticorps DER/EGFR, anticorps DER/faint little ball, anticorps DER/top, anticorps DER/torpedo, anticorps DER1, anticorps DEgfr, anticorps Degfr, anticorps Der, anticorps DmHD-33, anticorps Dmel\\CG10079, anticorps EFG-R, anticorps EGF-R, anticorps EGFR, anticorps EGFr, anticorps EGfr, anticorps EK2-6, anticorps Egf, anticorps Egf-r, anticorps EgfR, anticorps El, anticorps Elp, anticorps Elp-1, anticorps Elp-B1, anticorps Elp-B1RB1, anticorps HD-33, anticorps TOP, anticorps Torpedo/DER, anticorps Torpedo/Egfr, anticorps c-erbB, anticorps d-egf-r, anticorps dEGFR, anticorps dEGFR1, anticorps dEgfr, anticorps der, anticorps egfr, anticorps flb, anticorps l(2)05351, anticorps l(2)09261, anticorps l(2)57DEFa, anticorps l(2)57EFa, anticorps l(2)57Ea, anticorps mor1, anticorps top, anticorps top/DER, anticorps top/flb, anticorps torpedo/Egfr, anticorps torpedo/egfr, anticorps EGFR12, anticorps EGFR15, anticorps egfr1, anticorps Erbb2, anticorps ERBB, anticorps ERBB1, anticorps HER1, anticorps PIG61, anticorps mENA, anticorps ErbB-1, anticorps Errp, anticorps 9030024J15Rik, anticorps AI552599, anticorps Erbb, anticorps Errb1, anticorps Wa5, anticorps wa-2, anticorps wa2, anticorps epidermal growth factor receptor, anticorps Epidermal growth factor receptor, anticorps epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian), anticorps EGFR, anticorps Egfr, anticorps egfra, anticorps egfr1, anticorps LOC5564544
- Pathways
- Signalisation NF-kappaB, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
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