MUC1 anticorps (DTRP (Asp-Thr-Arg-Pro))
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- Antigène Voir toutes MUC1 Anticorps
- MUC1 (Mucin 1 (MUC1))
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Épitope
- DTRP (Asp-Thr-Arg-Pro)
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MUC1 est non-conjugé
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Purification
- Concentrated.
- Immunogène
- Human Milk Fat Globule Membranes
- Clone
- B24-1 (GP1-4)
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product MUC1 Anticorps primaire
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- Indications d'application
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Immunohistochemistry: (Paraffin/Frozen): 1:50.
Staining Procedure: Prolonged fixation in buffered formalin can destroy the epitope. The antibody may be used at a dilution of 1:50 in IHC. It is recommended that this product be used on frozen tissue sections or specimens. The optimal conditions should be determined by the individual laboratory. - Commentaires
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Cellular Localization: Cell Membrane, Cytoplasmic.
Recommended Positive Control: Breast Carcinoma - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.3 mg/ml.
- Buffer
- 20 mM Tris-Borate, 150 mM Sodium Chloride, dialyzed media RPMI 1640/D-MEM containing Fetal Bovine Serum, BMC-6 Carrier Polysaccharides, Carrier Protein, pH 7.5
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
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Cell membrane-associated mucins and their adhesion-modulating property." dans: Trends in biochemical sciences, Vol. 17, Issue 9, pp. 359-63, (1992) (PubMed).
: "Monoclonal antibodies against human milk-fat globule membranes detecting differentiation antigens of the mammary gland and its tumors." dans: International journal of cancer. Journal international du cancer, Vol. 34, Issue 2, pp. 197-206, (1984) (PubMed).
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Cell membrane-associated mucins and their adhesion-modulating property." dans: Trends in biochemical sciences, Vol. 17, Issue 9, pp. 359-63, (1992) (PubMed).
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- Antigène
- MUC1 (Mucin 1 (MUC1))
- Autre désignation
- EMA (MUC1 Produits)
- Synonymes
- anticorps CA 15-3, anticorps CD227, anticorps EMA, anticorps H23AG, anticorps KL-6, anticorps MAM6, anticorps MCKD1, anticorps MUC-1, anticorps MUC-1/SEC, anticorps MUC-1/X, anticorps MUC1/ZD, anticorps PEM, anticorps PEMT, anticorps PUM, anticorps Muc-1, anticorps mucin 1, cell surface associated, anticorps mucin 1, transmembrane, anticorps MUC1, anticorps Muc1
- Sujet
- Reacts with human high molecular weight sialomucin, episialin, mucin 1 (MUC-1), or polymorphic epithelial mucin (PEM). It recognizes the multiple protein epitope that is relatively insensitive to glycosylation. Therefore, it is very sensitive in the detection of episialin expression in different epithelial tissues.
- Poids moléculaire
- 265-400 kDa
- ID gène
- 4582
- Pathways
- Negative Regulation of intrinsic apoptotic Signaling
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