Factor VIII anticorps
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- Antigène Voir toutes Factor VIII (F8) Anticorps
- Factor VIII (F8) (Coagulation Factor VIII (F8))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Factor VIII est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Ascitic fluid
- Immunogène
- Purified recombinant fragment of F8 expressed in E. Coli.
- Clone
- 5E9B2
- Isotype
- IgG1
- Top Product
- Discover our top product F8 Anticorps primaire
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- Indications d'application
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Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - Restrictions
- For Research Use only
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- Format
- Liquid
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
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Elevated factor VIII in hereditary haemorrhagic telangiectasia (HHT): association with venous thromboembolism." dans: Thrombosis and haemostasis, Vol. 98, Issue 5, pp. 1031-9, (2007) (PubMed).
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Elevated factor VIII in hereditary haemorrhagic telangiectasia (HHT): association with venous thromboembolism." dans: Thrombosis and haemostasis, Vol. 98, Issue 5, pp. 1031-9, (2007) (PubMed).
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- Antigène
- Factor VIII (F8) (Coagulation Factor VIII (F8))
- Autre désignation
- F8 (F8 Produits)
- Synonymes
- anticorps fb61d02, anticorps wu:fb61d02, anticorps Cf-8, anticorps Cf8, anticorps FVIII, anticorps AHF, anticorps DXS1253E, anticorps F8B, anticorps F8C, anticorps HEMA, anticorps coagulation factor VIIi, anticorps coagulation factor VIII, anticorps coagulation factor VIII, procoagulant component, anticorps f7i, anticorps F8
- Sujet
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F8: coagulation factor VIII, procoagulant component. This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
Synonyms: AHF, F8B, F8C, HEMA, FVIII - ID gène
- 2157
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