FOXO1 anticorps
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- Antigène Voir toutes FOXO1 Anticorps
- FOXO1 (Forkhead Box O1 (FOXO1))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp FOXO1 est non-conjugé
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Application
- Immunohistochemistry (IHC)
- Specificité
- FKHR (Ab-319) antibody detects endogenous levels of total FKHR protein.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogène
- The antiserum was produced against synthesized non-phosphopeptide derived from human FKHR around the phosphorylation site of serine 319.
- Top Product
- Discover our top product FOXO1 Anticorps primaire
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- Indications d'application
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WB: 1:500~1:1000
IHC: 1:50~1:100. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100ug/100ul.
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms." dans: The Biochemical journal, Vol. 378, Issue Pt 3, pp. 839-49, (2004) (PubMed).
: "Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion." dans: The EMBO journal, Vol. 21, Issue 9, pp. 2263-71, (2002) (PubMed).
: "Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting." dans: The Biochemical journal, Vol. 354, Issue Pt 3, pp. 605-12, (2001) (PubMed).
: "Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence." dans: The Journal of biological chemistry, Vol. 274, Issue 24, pp. 17184-92, (1999) (PubMed).
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Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation- and 14-3-3-dependent and -independent mechanisms." dans: The Biochemical journal, Vol. 378, Issue Pt 3, pp. 839-49, (2004) (PubMed).
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- Antigène
- FOXO1 (Forkhead Box O1 (FOXO1))
- Autre désignation
- FKHR (FOXO1 Produits)
- Synonymes
- anticorps FKH1, anticorps FKHR, anticorps FOXO1A, anticorps FoxO1a.1, anticorps foxo1, anticorps zgc:153388, anticorps Fkhr, anticorps Foxo1a, anticorps AI876417, anticorps Afxh, anticorps Fkhr1, anticorps fkh1, anticorps fkhr, anticorps foxo1a, anticorps xFoxO1, anticorps FoxO1A, anticorps foxo1a.2, anticorps forkhead box O1, anticorps forkhead box O1 a, anticorps forkhead box O1 L homeolog, anticorps forkhead box O1 b, anticorps FOXO1, anticorps foxo1a, anticorps Foxo1, anticorps foxo1, anticorps foxo1.L, anticorps foxo1b
- Pathways
- Signalisation PI3K-Akt, Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling
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