Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of Bacteria: Staphylococcus aureus FnbA (Fibronectin-binding protein A)
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For Research Use only
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Diep, Gill, Chang, Phan, Chen, Davidson, Lin, Lin, Carleton, Mongodin, Sensabaugh, Perdreau-Remington: "Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus." dans: Lancet, Vol. 367, Issue 9512, pp. 731-9, (2006) (PubMed).
Gill, Fouts, Archer, Mongodin, Deboy, Ravel, Paulsen, Kolonay, Brinkac, Beanan, Dodson, Daugherty, Madupu, Angiuoli, Durkin, Haft, Vamathevan, Khouri, Utterback, Lee, Dimitrov, Jiang, Qin, Weidman, Tran, Kang, Hance, Nelson, Fraser: "Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain." dans: Journal of bacteriology, Vol. 187, Issue 7, pp. 2426-38, (2005) (PubMed).
Antigène
FnbA
Sujet
FnbA (Fibronectin-binding protein A) promotes bacterial attachment to multiple substrates, such as fibronectin (Fn), fibrinogen (Fg), elastin peptides and tropoelastin. This confers to S.aureus the ability to invade endothelial cells. FnbA (Fibronectin-binding protein A) promotes adherence to and aggregation of activated platelets. FnbA (Fibronectin-binding protein A) is secreted, cell wall Peptidoglycan-anchor.