ErbB2/Her2 anticorps
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- Antigène Voir toutes ErbB2/Her2 Anticorps
- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp ErbB2/Her2 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- Ascitic fluid
- Immunogène
- Purified recombinant fragment of HER-2 expressed in E. Coli.
- Clone
- 9B9D8
- Isotype
- IgG2b
- Top Product
- Discover our top product ErbB2/Her2 Anticorps primaire
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- Indications d'application
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Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - Restrictions
- For Research Use only
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- Format
- Liquid
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
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When is a tumor marker ready for prime time? A case study of c-erbB-2 as a predictive factor in breast cancer." dans: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 19, Issue 8, pp. 2334-56, (2001) (PubMed).
: "Relationship between c-erbB-2 and other tumor characteristics in breast cancer prognosis." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 6, Issue 12, pp. 4745-54, (2001) (PubMed).
: "Plasma c-erbB-2 levels in breast cancer patients: prognostic significance in predicting response to chemotherapy." dans: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 16, Issue 7, pp. 2409-16, (1998) (PubMed).
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When is a tumor marker ready for prime time? A case study of c-erbB-2 as a predictive factor in breast cancer." dans: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 19, Issue 8, pp. 2334-56, (2001) (PubMed).
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- Antigène
- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
- Autre désignation
- HER-2 (ErbB2/Her2 Produits)
- Synonymes
- anticorps CD340, anticorps HER-2, anticorps HER-2/neu, anticorps HER2, anticorps MLN 19, anticorps NEU, anticorps NGL, anticorps TKR1, anticorps Erbb-2, anticorps Neu, anticorps c-erbB2, anticorps c-neu, anticorps mKIAA3023, anticorps wu:fv70f10, anticorps zgc:63601, anticorps erb2, anticorps erb-b2 receptor tyrosine kinase 2, anticorps ERBB2, anticorps Erbb2, anticorps erbb2
- Sujet
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The C-erbB-2 (HER-2/neu) gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Amplification or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. High levels of c-erbB-2 were associated with estrogen receptor (ER) and progesterone receptor negativity. Overexpression of the c-erbB-2 oncogene has been shown to be associated with poor prognosis in ovarian and breast cance, The level of increased Neu expression can be a predictor of disease prognosis
Synonyms: HER-2, C-erB-2, erbB-2 - ID gène
- 2064
- Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
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