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MAP2K3 anticorps (C-Term)
MAP2K3
Reactivité: Humain, Rat
WB, IHC (p), ICC
Polyclonal
unconjugated
Détail du produit anti-MAP2K3 anticorps
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Antigène
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MAP2K3
(Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
Épitope
Tous les épitopes à travers MAP2K3 Anticorps.
AA 320-334, C-Term
Reactivité
Toutes les réactivités sur MAP2K3 Anticorps
Humain, Rat
Hôte
Veuillez nous consulter SVP
Clonalité
Toutes les clonalités sur MAP2K3 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers MAP2K3 Anticorps
Cet anticorp MAP2K3 est non-conjugé
Application
Tous les applications à travers MAP2K3 Anticorps.
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
Immunogène
A synthetic peptide corresponding to a sequence at the C-terminal of human MAP2K3 (320-334 aa), identical to the related mouse and rat sequence.
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Alternatives
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Information d'application
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Restrictions
For Research Use only
Stockage
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Reconstitution
0.2ml of distilled water will yield a concentration of 500µg/ml.
Buffer
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
Agent conservateur
Thimerosal (Merthiolate), Sodium azide
Stock
-20 °C
Références pour anticorps anti-MAP2K3 (ABIN966513)
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Rampoldi, Zimbello, Bortoluzzi, Tiso, Valle, Lanfranchi, Danieli : "Chromosomal localization of four MAPK signaling cascade genes: MEK1, MEK3, MEK4 and MEKK5. " dans: Cytogenetics and cell genetics , Vol. 78 , Issue 3-4 , pp. 301-3 , (1998 ) (PubMed ).
Détails sur MAP2K3
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Antigène
MAP2K3
(Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
Autre désignation
MAP2K3 (MAP2K3 Produits )
Synonymes
anticorps MAPKK3, anticorps MEK3, anticorps MKK3, anticorps PRKMK3, anticorps SAPKK-2, anticorps SAPKK2, anticorps AW212142, anticorps Prkmk3, anticorps mMKK3b, anticorps Mkk3, anticorps mitogen-activated protein kinase kinase 3, anticorps mitogen activated protein kinase kinase 3, anticorps MAP kinase activator XMEK3, anticorps MAP2K3, anticorps Map2k3, anticorps map2k3
Sujet
Dual specificity mitogen-activated protein kinase kinase 3 is an enzyme that in humans is encoded by the MAP2K3 gene. The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. Rampoldi et al. (1997) localized the MAP2K3 gene to 17q11.2.
Pathways
Signalisation MAPK , Signalisation TLR , Activation of Innate immune Response , Toll-Like Receptors Cascades , Autophagy , Signaling Events mediated by VEGFR1 and VEGFR2
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