Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of mouse Mct1 (Monocarboxylate transporter 1)
Koehler-Stec, Simpson, Vannucci, Landschulz, Landschulz: "Monocarboxylate transporter expression in mouse brain." dans: The American journal of physiology, Vol. 275, Issue 3 Pt 1, pp. E516-24, (1998) (PubMed).
Carpenter, Poole, Halestrap: "Cloning and sequencing of the monocarboxylate transporter from mouse Ehrlich Lettré tumour cell confirms its identity as MCT1 and demonstrates that glycosylation is not required for MCT1 function." dans: Biochimica et biophysica acta, Vol. 1279, Issue 2, pp. 157-63, (1996) (PubMed).
Antigène
MCTS1
(Malignant T Cell Amplified Sequence 1 (MCTS1))
Mct1 (Monocarboxylate transporter 1) functions as a Proton-linked monocarboxylate transporter. Mct1 (Monocarboxylate transporter 1) catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Mct1 (Monocarboxylate transporter 1) is a multi-pass membrane protein. Major isoform present in tumor cells, erythrocytes. Mct1 belongs to the major facilitator superfamily and Monocarboxylate porter (TC 2.A.1.13) family. Synonyms: Slc16a1 (Solute carrier family 16 member 1)