Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Zebisch, Staber, Delavar, Bodner, Hiden, Fischereder, Janakiraman, Linkesch, Auner, Emberger, Windpassinger, Schimek, Hoefler, Troppmair, Sill: "Two transforming C-RAF germ-line mutations identified in patients with therapy-related acute myeloid leukemia." dans: Cancer research, Vol. 66, Issue 7, pp. 3401-8, (2006) (PubMed).
Luciano, Hsu, Channavajhala, Lin, Cuozzo: "Phosphorylation of threonine 290 in the activation loop of Tpl2/Cot is necessary but not sufficient for kinase activity." dans: The Journal of biological chemistry, Vol. 279, Issue 50, pp. 52117-23, (2004) (PubMed).
Gopalbhai, Jansen, Beauregard, Whiteway, Dumas, Wu, Meloche: "Negative regulation of MAPKK by phosphorylation of a conserved serine residue equivalent to Ser212 of MEK1." dans: The Journal of biological chemistry, Vol. 278, Issue 10, pp. 8118-25, (2003) (PubMed).
Wang, Jin, Wong, Feng, Wong, Tsao: "MAD2-induced sensitization to vincristine is associated with mitotic arrest and Raf/Bcl-2 phosphorylation in nasopharyngeal carcinoma cells." dans: Oncogene, Vol. 22, Issue 1, pp. 109-16, (2003) (PubMed).
Antigène
MEK1 (MAP2K1)
(Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))