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NFKB1 anticorps
NFKB1
Reactivité: Humain
WB, IHC, ELISA, FACS
Hôte: Souris
Monoclonal
5D10
unconjugated
Détail du produit anti-NFKB1 anticorps
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Antigène
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NFKB1
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))
Reactivité
Toutes les réactivités sur NFKB1 Anticorps
Humain
Hôte
Toutes les hôtes sur NFKB1 Anticorps
Souris
Clonalité
Toutes les clonalités sur NFKB1 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers NFKB1 Anticorps
Cet anticorp NFKB1 est non-conjugé
Application
Tous les applications à travers NFKB1 Anticorps.
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
Purification
Ascitic fluid
Immunogène
Purified recombinant fragment of human NFKB1 expressed in E. Coli.
Clone
5D10
Isotype
IgG2a
Top Product
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Alternatives
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Information d'application
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Indications d'application
Western Bloting: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: Propose dilution 1/10000. Not yet tested in other applications. Determining optimal working dilutions by titration test.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Détails sur NFKB1
(cache)
Antigène
NFKB1
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))
Autre désignation
NFKB1 (NFKB1 Produits )
Synonymes
anticorps GKLP, anticorps NKTL, anticorps NTKL, anticorps P105, anticorps TAPK, anticorps TEIF, anticorps TRAP, anticorps EBP-1, anticorps KBF1, anticorps NF-kB1, anticorps NF-kappa-B, anticorps NF-kappaB, anticorps NFKB-p105, anticorps NFKB-p50, anticorps NFkappaB, anticorps p105, anticorps p50, anticorps NF-kB, anticorps NF-KB1, anticorps ebp-1, anticorps kbf1, anticorps nf-kappa-b, anticorps nf-kappaB, anticorps nfkb-p105, anticorps nfkb-p50, anticorps NF-kappaB1, anticorps p50/p105, anticorps BICDR-1, anticorps bicdr1, anticorps ccdc64, anticorps SCY1 like pseudokinase 1, anticorps nuclear factor kappa B subunit 1, anticorps nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 L homeolog, anticorps nuclear factor NF-kappa-B p105 subunit, anticorps nucleoporin 107, anticorps nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105, anticorps nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, anticorps SCYL1, anticorps NFKB1, anticorps Nfkb1, anticorps nfkb1.L, anticorps CpipJ_CPIJ012236, anticorps Nup107, anticorps nfkb1
Sujet
This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. Synonyms: p50, KBF1, p105, EBP1, MGC54151, NFKB-p50, NFkappaB, NF-kappaB, NFKBp105, NF-kappa-B
Poids moléculaire
50kDa/105kDa
ID gène
4790
Pathways
Signalisation p53 , Signalisation NF-kappaB , Signalisation RTK , TCR Signaling , Signalisation TLR , Fc-epsilon Receptor Signaling Pathway , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Myometrial Relaxation and Contraction , Regulation of Carbohydrate Metabolic Process , Hepatitis C , Toll-Like Receptors Cascades , BCR Signaling , S100 Proteins
Vus récemment
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