NOS1 anticorps (C-Term)
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- Antigène Voir toutes NOS1 Anticorps
- NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NOS1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Souris, Rat (Rattus)
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
- Rabbit IgG polyclonal antibody for Nitric oxide synthase, brain (NOS1) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
- Immunogène
- A synthetic peptide corresponding to a sequence at the C-terminal of human NOS1 , identical to the related mouse and rat sequences.< br/>Immunogen was affinity purified.
- Isotype
- IgG
- Top Product
- Discover our top product NOS1 Anticorps primaire
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Agent conservateur
- Sodium azide, Thimerosal (Merthiolate)
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.
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- Antigène
- NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))
- Autre désignation
- Nitric oxide synthase, brain (NOS1 Produits)
- Synonymes
- anticorps NOS1, anticorps IHPS1, anticorps N-NOS, anticorps NC-NOS, anticorps NOS, anticorps bNOS, anticorps nNOS, anticorps 2310005C01Rik, anticorps NO, anticorps NOS-I, anticorps Nos-1, anticorps nos, anticorps ihps1, anticorps nnos, anticorps nos1, anticorps nos1-A, anticorps nanos C2HC-type zinc finger 1, anticorps nitric oxide synthase 1, anticorps nitric oxide synthase 1, neuronal, anticorps nitric oxide synthase 1 (neuronal), anticorps nitric oxide synthase 1 L homeolog, anticorps NANOS1, anticorps NOS1, anticorps Nos1, anticorps nos1, anticorps nos1.L
- Sujet
- Nitric Oxide Synthase 1 (NOS1,neuronal NOS,nNOS1) is a messenger molecule, mediating the effect of endothelium-derived relaxing factor in blood vessels and the cytotoxic actions of macrophages, and playing a part in neuronal communication in the brain. It may be involved in neuronal cell death and damage in neurological illness. nNOS1 localized to the 12q24. 2 region of human chromosome 12. It splice variant, expressed in testis, that encodes an NH2-terminal truncated protein of 1098 amino acids. nNOS cDNA clones were shown to contain different 5' terminal exons spliced to a common exon 2. Genomic cloning and sequence analysis demonstrate that the unique exons are positioned within 300 bp of each other but separated from exon 2 by an intron that is at least 20 kb in length. The neuronal isoform of nitric oxide synthase is highly expressed in mammalian skeletal muscle, it suggested a specific role for NOS1 in the local metabolic inhibition of alpha-adrenergic vasoconstriction in active skeletal muscle. The novel gaseous neuromediator nitric oxide is thought to play an important role in development and plasticity. Despite this, gene-knockout mice lacking neuronal (Type I) nitric oxide synthase exhibit relatively normal brain development and behavior.
- Pathways
- Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction
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