OGG1 anticorps (acLys338, acLys341, C-Term)

N° du produit ABIN966716

Détail du produit anti-OGG1 anticorps

Antigène: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Épitope: acLys338, acLys341, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OGG1 est non-conjugé

Application: Immunohistochemistry (IHC)

Immunogène: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human OGG1 (N-glycosylase/DNA lyase)

Information d'application

Restrictions: For Research Use only

Stockage

Stock: 4 °C

Références pour anticorps anti-OGG1 (ABIN966716)

Aburatani, Hippo, Ishida, Takashima, Matsuba, Kodama, Takao, Yasui, Yamamoto, Asano: "Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue." dans: Cancer research, Vol. 57, Issue 11, pp. 2151-6, (1997) (PubMed).

Rosenquist, Zharkov, Grollman: "Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 14, pp. 7429-34, (1997) (PubMed).

Roldán-Arjona, Wei, Carter, Klungland, Anselmino, Wang, Augustus, Lindahl: "Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 15, pp. 8016-20, (1997) (PubMed).

Kuo, Sklar: "Augmented expression of a human gene for 8-oxoguanine DNA glycosylase (MutM) in B lymphocytes of the dark zone in lymph node germinal centers." dans: The Journal of experimental medicine, Vol. 186, Issue 9, pp. 1547-56, (1997) (PubMed).

Bjorâs, Luna, Johnsen, Hoff, Haug, Rognes, Seeberg: "Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites." dans: The EMBO journal, Vol. 16, Issue 20, pp. 6314-22, (1997) (PubMed).

Détails sur OGG1

Antigène: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Autre désignation: OGG1 (OGG1 Produits)

Synonymes: anticorps OGG1, anticorps zgc:158858, anticorps 8-oxoguanine-DNA glycosylase 1, anticorps ARABIDOPSIS 8-OXOGUANINE-DNA GLYCOSYLASE 1, anticorps ATOGG1, anticorps F8K7.14, anticorps F8K7_14, anticorps 19.m02329, anticorps DDBDRAFT_0184479, anticorps DDBDRAFT_0233024, anticorps DDB_0184479, anticorps DDB_0233024, anticorps ogg1, anticorps Tb04.1H19.930, anticorps HMMH, anticorps HOGG1, anticorps MUTM, anticorps OGH1, anticorps Mmh, anticorps 8-oxoguanine DNA glycosylase, anticorps 8-oxoguanine DNA glycosylase L homeolog, anticorps 8-oxoguanine-DNA glycosylase 1, anticorps 8-OXOGUANINE DNA GLYCOSYLASE, anticorps putative 8-oxoguanine DNA glycosylase, anticorps 8-oxoguanine DNA-glycosylase, anticorps N-glycosylase/DNA lyase OGG1, anticorps 8-oxoguanine DNA-glycosylase 1, anticorps OGG1, anticorps ogg1.L, anticorps ogg1, anticorps ECU08_0770, anticorps CA_C2707, anticorps BBOV_I004290, anticorps Smp_074010.1, anticorps LOC9329243, anticorps Tb927.4.2480, anticorps Ogg1

Sujet: DNA repair enzyme that incises DNA at 8-oxoG residues. OGG1 (N-glycosylase/DNA lyase) excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-Nmethylformamidopyrimidine (FAPY) from damaged DNA. OGG1 has a beta-lyase activity that nicks DNA 3' to the lesion. Defects in OGG1 are associated with tumor formation.Defects in OGG1 are a cause of renal cell carcinoma OGG1 belongs to the type-1 OGG1 family.
Synonyms: MMH, MUTM, OGH1

Pathways: Réparation de l'ADN