PKC (Ab-641) antibody detects endogenous levels of total PKC protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogène
The antiserum was produced against synthesized non-phosphopeptide derived from human PKC around the phosphorylation site of threonine 641 (E-L-TP-P-T).
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Fu, Deng, Zhao, Li, Zhou, Zhang: "Distinct expression patterns of hedgehog ligands between cultured and primary colorectal cancers are associated with aberrant methylation of their promoters." dans: Molecular and cellular biochemistry, Vol. 337, Issue 1-2, pp. 185-92, (2010) (PubMed).
Zhang, Liao, Dufau et al.: "Phosphatidylinositol 3-kinase/protein kinase Czeta-induced phosphorylation of Sp1 and p107 repressor release have a critical role in histone deacetylase inhibitor-mediated derepression [corrected] of ..." dans: Molecular and cellular biology, Vol. 26, Issue 18, pp. 6748-61, (2006) (PubMed).
Castoria, Migliaccio, Di Domenico, Lombardi, de Falco, Varricchio, Bilancio, Barone, Auricchio: "Role of atypical protein kinase C in estradiol-triggered G1/S progression of MCF-7 cells." dans: Molecular and cellular biology, Vol. 24, Issue 17, pp. 7643-53, (2004) (PubMed).
Marcil, Harbour, Houle, Naccache, Bourgoin: "Monosodium urate-crystal-stimulated phospholipase D in human neutrophils." dans: The Biochemical journal, Vol. 337 ( Pt 2), pp. 185-92, (1999) (PubMed).
Bornancin, Parker: "Phosphorylation of threonine 638 critically controls the dephosphorylation and inactivation of protein kinase Calpha." dans: Current biology : CB, Vol. 6, Issue 9, pp. 1114-23, (1997) (PubMed).