Cet anticorp Phospholipase C gamma 2 est non-conjugé
Application
Immunohistochemistry (IHC)
Specificité
PLC2 (Ab-753) antibody detects endogenous levels of total PLC2 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogène
The antiserum was produced against synthesized non-phosphopeptide derived from human PLC2 around the phosphorylation site of tyrosine 753 (S-L-YP-D-V).
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Kim, Sekiya, Poulin, Bae, Rhee: "Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2." dans: Molecular and cellular biology, Vol. 24, Issue 22, pp. 9986-99, (2004) (PubMed).
Suzuki-Inoue, Wilde, Andrews, Auger, Siraganian, Sekiya, Rhee, Watson: "Glycoproteins VI and Ib-IX-V stimulate tyrosine phosphorylation of tyrosine kinase Syk and phospholipase Cgamma2 at distinct sites." dans: The Biochemical journal, Vol. 378, Issue Pt 3, pp. 1023-9, (2004) (PubMed).