RAB25 anticorps

N° du produit ABIN966930

Détail du produit anti-RAB25 anticorps

Antigène: RAB25 (RAB25, Member RAS Oncogene Family (RAB25))

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Monoclonal

Conjugué: Cet anticorp RAB25 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Specificité: Ni-NTA purified recombinant Rab25 expressed in E. Coli strain BL21 (DE3)

Purification: Antibodies are purified by protein A affinity chromatography

Isotype: IgG2a

Information d'application

Indications d'application: Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.2%BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-RAB25 (ABIN966930)

Goldenring, Shen, Vaughan, Modlin: "Identification of a small GTP-binding protein, Rab25, expressed in the gastrointestinal mucosa, kidney, and lung." dans: The Journal of biological chemistry, Vol. 268, Issue 25, pp. 18419-22, (1993) (PubMed).

Détails sur RAB25

Antigène: RAB25 (RAB25, Member RAS Oncogene Family (RAB25))

Autre désignation: Rab25 (RAB25 Produits)

Sujet: Members of the Ras-related superfamily of GTP binding proteins, which includes Ras, Rho, Rab and ARF subfamilies, exhibit 30-50% similarity with Ras p21. Rab proteins play an important role for either in endocytosis or in biosynthetic protein transport. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% similar to Rab proteins, is associated with secretory vesicles. Rab proteins located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Rab25 was cloned from a gastric parietal cell cDNA library and is expressed in epithelial tissues such as the gastrointestinal mucosae, kidney, and lung, which encoded a protein of 28 kDa

ID gène: 57111