SLUG anticorps (C-Term)
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- Antigène Voir toutes SLUG (SNAI2) Anticorps
- SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SLUG est non-conjugé
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Application
- Immunohistochemistry (IHC)
- Immunogène
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to near C-terminal residues of human SNAI2
- Top Product
- Discover our top product SNAI2 Anticorps primaire
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- Restrictions
- For Research Use only
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- Stock
- 4 °C
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Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer." dans: Carcinogenesis, Vol. 30, Issue 8, pp. 1459-68, (2009) (PubMed).
: "p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug." dans: Nature cell biology, Vol. 11, Issue 6, pp. 694-704, (2009) (PubMed).
: "Requirement of the Akt/beta-catenin pathway for uterine carcinosarcoma genesis, modulating E-cadherin expression through the transactivation of slug." dans: The American journal of pathology, Vol. 174, Issue 6, pp. 2107-15, (2009) (PubMed).
: "Human Slug is a repressor that localizes to sites of active transcription." dans: Molecular and cellular biology, Vol. 20, Issue 14, pp. 5087-95, (2000) (PubMed).
: "SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein." dans: Molecular cell, Vol. 4, Issue 3, pp. 343-52, (1999) (PubMed).
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Snail2 cooperates with Snail1 in the repression of vitamin D receptor in colon cancer." dans: Carcinogenesis, Vol. 30, Issue 8, pp. 1459-68, (2009) (PubMed).
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- Antigène
- SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
- Autre désignation
- SNAI2 (SNAI2 Produits)
- Synonymes
- anticorps Slug, anticorps Slugh, anticorps Snail2, anticorps snail family transcriptional repressor 2, anticorps snail family zinc finger 2, anticorps Snai2
- Sujet
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SNAI2 is a member of the Snail family of C2H2-type zinc finger transcription factors. The SNAI2 protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress Ecadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this SNAI2 gene may be associated with sporatic cases of neural tube defects.
Synonyms: MGC10182, SLUG, SLUGH1, WS2D
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