VAV1
Reactivité: Humain
WB, IHC, ICC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 1:500~1:1000.
Restrictions
For Research Use only
Format
Liquid
Concentration
100ug/100ul.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Amarasinghe, Rosen: "Acidic region tyrosines provide access points for allosteric activation of the autoinhibited Vav1 Dbl homology domain." dans: Biochemistry, Vol. 44, Issue 46, pp. 15257-68, (2005) (PubMed).
Charvet, Canonigo, Billadeau, Altman: "Membrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76." dans: The Journal of biological chemistry, Vol. 280, Issue 15, pp. 15289-99, (2005) (PubMed).
Miura-Shimura, Duan, Rao, Reddi, Shimura, Rottapel, Druker, Tsygankov, Band, Band: "Cbl-mediated ubiquitinylation and negative regulation of Vav." dans: The Journal of biological chemistry, Vol. 278, Issue 40, pp. 38495-504, (2003) (PubMed).
Kuhne, Ku, Weiss: "A guanine nucleotide exchange factor-independent function of Vav1 in transcriptional activation." dans: The Journal of biological chemistry, Vol. 275, Issue 3, pp. 2185-90, (2000) (PubMed).