CK1 epsilon anticorps (AA 248-414)

N° du produit ABIN967975

Détail du produit anti-CK1 epsilon anticorps

Antigène: CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))

Épitope: AA 248-414

Reactivité: Humain, Souris, Rat, Chien, Poulet

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CK1 epsilon est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Réactivité croisée: Souris, Rat (Rattus), Poulet, Chien

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Please refer to us for technical protocols.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Human Casein Kinase Iepsilon aa. 248-414

Clone: 1-Casein Kinase Iepsilon

Isotype: IgG1

Information d'application

Commentaires:

Related Products: ABIN968536, ABIN967389

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store undiluted at -20°C.

Références pour anticorps anti-CK1 epsilon (ABIN967975)

Akashi, Tsuchiya, Yoshino, Nishida: "Control of intracellular dynamics of mammalian period proteins by casein kinase I epsilon (CKIepsilon) and CKIdelta in cultured cells." dans: Molecular and cellular biology, Vol. 22, Issue 6, pp. 1693-703, (2002) (PubMed).

Kishida, Hino Si, Michiue, Yamamoto, Kishida, Fukui, Asashima, Kikuchi: "Synergistic activation of the Wnt signaling pathway by Dvl and casein kinase Iepsilon." dans: The Journal of biological chemistry, Vol. 276, Issue 35, pp. 33147-55, (2001) (PubMed).

Peters, McKay, McKay, Graff: "Casein kinase I transduces Wnt signals." dans: Nature, Vol. 401, Issue 6751, pp. 345-50, (1999) (PubMed).

Fish, Cegielska, Getman, Landes, Virshup: "Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family." dans: The Journal of biological chemistry, Vol. 270, Issue 25, pp. 14875-83, (1995) (PubMed).

Détails sur CK1 epsilon

Antigène: CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))

Autre désignation: Casein Kinase Iepsilon (CSNK1E Produits)

Synonymes: anticorps CKIepsilon, anticorps HCKIE, anticorps CKIe, anticorps ck1-epsilon, anticorps ck1epsilon, anticorps hckie, anticorps dco, anticorps fj38c01, anticorps wu:fj38c01, anticorps wu:fj62a04, anticorps zgc:77310, anticorps AI426939, anticorps AI551861, anticorps AW457082, anticorps CK1epsilon, anticorps KC1epsilon, anticorps tau, anticorps ckie, anticorps CSNK1E, anticorps Csnk1e, anticorps CKI-epsilon, anticorps 0538/13, anticorps 0915/10, anticorps 1396/02, anticorps 1447/01, anticorps 1460/09, anticorps CG2048, anticorps CK1delta/epsilon, anticorps DBT, anticorps DBT/CK1epsilon, anticorps DCO, anticorps DCO/CKIe, anticorps Dbt, anticorps Dco, anticorps Dco/CK1, anticorps Dmel\CG2048, anticorps dCKIepsilon, anticorps dbt, anticorps dco-1, anticorps ddbt, anticorps l(3)S053813, anticorps l(3)S144701, anticorps l(3)dco, anticorps l(3)dco-1, anticorps l(3)discs overgrown, anticorps l(3)discs overgrown-1, anticorps l(3)j3B9, anticorps l(3)rK215, anticorps casein kinase 1 epsilon, anticorps casein kinase 1, epsilon, anticorps casein kinase 1 epsilon L homeolog, anticorps casein kinase I isoform epsilon, anticorps casein kinase I epsilon, anticorps casein kinase I, anticorps LOC400927-CSNK1E readthrough, anticorps discs overgrown, anticorps CSNK1E, anticorps csnk1e, anticorps Csnk1e, anticorps csnk1e.L, anticorps LOC443240, anticorps NAEGRDRAFT_82890, anticorps LOC100407384, anticorps LOC100523244, anticorps LOC100607246, anticorps LOC100727500, anticorps LOC400927-CSNK1E, anticorps dco

Sujet: Casein Kinase Iepsilon (CKIepsilon) is a product of a family of proteins involved in the regulation of various cytoplasmic and nuclear processes including DNA replication and repair. CKIepsilon is a 47.3 kDa serine/threonine kinase that plays a role similar to previously described CKI isoforms. It phosphorylates known CKI substrates, including a CKI-specific peptide. In addition, it is inhibited by CKI-7, an inhibitor of other CKI isoforms. CKIepsilon contains a core kinase domain of 285 amino acids which is 53-98% identical to other isoforms and is most similiar in structure to CKIdelta. Since various human and yeast CKI proteins exhibit both sequence and functional similarities, CKIepsilon may be involved in mammalian DNA metabolism.

Poids moléculaire: 47 kDa

Pathways: Signalisation Hedgehog, M Phase