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FKBP10 anticorps (AA 434-576)

FKBP10 Reactivité: Humain, Souris, Rat WB, IHC, IP, IF Hôte: Souris Monoclonal 25-FKBP65 unconjugated
N° du produit ABIN968087
  • Antigène Voir toutes FKBP10 Anticorps
    FKBP10 (FK506 Binding Protein 10, 65 KDa (FKBP10))
    Épitope
    • 10
    • 9
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 434-576
    Reactivité
    • 32
    • 9
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 29
    • 4
    Souris
    Clonalité
    • 30
    • 3
    Monoclonal
    Conjugué
    • 23
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp FKBP10 est non-conjugé
    Application
    • 31
    • 17
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
     Réactivité croisée
    Rat (Rattus), Humain
    Attributs du produit
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Please refer to us for technical protocols.
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogène
    Mouse FKBP65 aa. 434-576
    Clone
    25-FKBP65
    Isotype
    IgG1
    Top Product
    Discover our top product FKBP10 Anticorps primaire
  • Commentaires

    Related Products: ABIN967389, ABIN968539

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store undiluted at -20°C.
  • Patterson, Schaub, Coleman, Davis: "Developmental regulation of FKBP65. An ER-localized extracellular matrix binding-protein." dans: Molecular biology of the cell, Vol. 11, Issue 11, pp. 3925-35, (2001) (PubMed).

    Coss, Winterstein, Sowder, Simek: "Molecular cloning, DNA sequence analysis, and biochemical characterization of a novel 65-kDa FK506-binding protein (FKBP65)." dans: The Journal of biological chemistry, Vol. 270, Issue 49, pp. 29336-41, (1996) (PubMed).

  • Antigène
    FKBP10 (FK506 Binding Protein 10, 65 KDa (FKBP10))
    Autre désignation
    FKBP65 (FKBP10 Produits)
    Synonymes
    anticorps fkbp10, anticorps MGC82987, anticorps FKBP10, anticorps wu:fc27c03, anticorps AI325255, anticorps FKBP-10, anticorps FKBP-65, anticorps FKBP65, anticorps Fkbp-rs1, anticorps Fkbp1-rs, anticorps Fkbp6, anticorps Fkbprp, anticorps OI11, anticorps OI6, anticorps PPIASE, anticorps hFKBP65, anticorps FK506 binding protein 1A, 12kDa, anticorps FK506 binding protein 10, anticorps FK506 binding protein 10b, anticorps FK506 binding protein 10 L homeolog, anticorps fkbp1a, anticorps FKBP10, anticorps fkbp10b, anticorps fkbp10.L, anticorps fkbp10, anticorps Fkbp10
    Sujet
    FK506, one of multiple potent compounds that block T cell proliferation, is used for immunosuppressive therapy. Several FK506-binding proteins (FKBPs) have been identified in the search for intracellular targets for FK506. These include FKBP12, FKBP13, FKBP51, and FKBP52. The immunosuppressive effects of FK506 and FKBPs result from the inhibition of the calcineurin phosphatase, a well known component of the signaling cascade leading to IL-2 production. FKBP65 is another member of the FKBP protein family and contains the characteristic peptidylprolyl cis-trans-isomerase activity. FKBP65 has been reported to be expressed in the lung, testis, brain, heart, and spleen. Although it has a predicted molecular weight of 65 kDa, FKBP65 has been observed to migrate ranging from 68-72 kDa in SDS electrophoresis gels, perhaps, due to glycosylation and/or phosphorylation.
    Synonyms: FK506 Binding Protein-65
    Poids moléculaire
    68-72 kDa
    Pathways
    SARS-CoV-2 Protein Interactome
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