NINJ1 anticorps (AA 1-152)

N° du produit ABIN968172

Détail du produit anti-NINJ1 anticorps

Antigène: NINJ1 (Ninjurin 1 (NINJ1))

Épitope: AA 1-152

Reactivité: Humain, Souris, Rat, Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NINJ1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Réactivité croisée: Chien, Rat (Rattus), Souris

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Human Ninjurin aa. 1-152

Clone: 50-Ninjurin

Isotype: IgG2a

Information d'application

Commentaires:

Related Products: ABIN968587, ABIN967389

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store undiluted at -20° C.

Références pour anticorps anti-NINJ1 (ABIN968172)

Chen, Coustan-Smith, Suzuki, Neale, Mihara, Pui, Campana: "Identification of novel markers for monitoring minimal residual disease in acute lymphoblastic leukemia." dans: Blood, Vol. 97, Issue 7, pp. 2115-20, (2001) (PubMed).

Araki, Zimonjic, Popescu, Milbrandt: "Mechanism of homophilic binding mediated by ninjurin, a novel widely expressed adhesion molecule." dans: The Journal of biological chemistry, Vol. 272, Issue 34, pp. 21373-80, (1997) (PubMed).

Araki, Milbrandt: "Ninjurin, a novel adhesion molecule, is induced by nerve injury and promotes axonal growth." dans: Neuron, Vol. 17, Issue 2, pp. 353-61, (1996) (PubMed).

Détails sur NINJ1

Antigène: NINJ1 (Ninjurin 1 (NINJ1))

Autre désignation: Ninjurin (NINJ1 Produits)

Synonymes: anticorps nin1, anticorps MGC79511, anticorps ninjurin, anticorps NIN1, anticorps NINJURIN, anticorps AU024536, anticorps ninjurin 1, anticorps ninjurin 1 L homeolog, anticorps NINJ1, anticorps ninj1, anticorps ninj1.L, anticorps Ninj1

Sujet: Ninjurin is a protein whose expression is dramatically increased after sciatic nerve transection and crush injuries. The Ninjurin gene encodes for a protein of 152 amino acids with two putative transmembrane domains. Ninjurin was iodinated in vivo and promoted the aggregation of Jurkat cells expressing Ninjurin, indicating a portion of Ninjurin is exposed to the cell surface. The adhesive properties of Ninjurin were energy and temperature dependent, required Ca2+ and Mg2+, and the integrity of the cytoskeleton. Also, the adhesion domain of Ninjurin is located at the extracellular NH2-terminal domain. Although its predicted mass is 16 kDa, Ninjurin migrates as a 18-22 kDa protein in SDS-PAGE, depending on the cell line or tissue. mRNA analysis revealed that Ninjurin is widely expressed with the highest levels in liver, thymus, heart, and the lowest level in brain.

Poids moléculaire: 18-22 kDa