TFCP2 anticorps (AA 205-414)

N° du produit ABIN968193

Détail du produit anti-TFCP2 anticorps

Antigène: TFCP2 (Transcription Factor CP2 (TFCP2))

Épitope: AA 205-414

Reactivité: Humain, Souris, Rat, Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TFCP2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Réactivité croisée: Souris, Rat (Rattus), Chien

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Human LSF aa. 205-414

Clone: 14-LSF

Isotype: IgG1

Information d'application

Commentaires:

Related Products: ABIN968551, ABIN967389

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store undiluted at -20° C.

Références pour anticorps anti-TFCP2 (ABIN968193)

Volker, Rameh, Zhu, DeCaprio, Hansen: "Mitogenic stimulation of resting T cells causes rapid phosphorylation of the transcription factor LSF and increased DNA-binding activity." dans: Genes & development, Vol. 11, Issue 11, pp. 1435-46, (1997) (PubMed).

Shirra, Zhu, Huang, Pallas, Hansen: "One exon of the human LSF gene includes conserved regions involved in novel DNA-binding and dimerization motifs." dans: Molecular and cellular biology, Vol. 14, Issue 8, pp. 5076-87, (1994) (PubMed).

Détails sur TFCP2

Antigène: TFCP2 (Transcription Factor CP2 (TFCP2))

Autre désignation: LSF (TFCP2 Produits)

Synonymes: anticorps cp2, anticorps lsf, anticorps sef, anticorps lbp-1c, anticorps tfcp2c, anticorps MGC75945, anticorps TFCP2, anticorps lbp1c, anticorps lsf1d, anticorps TCFCP2, anticorps LBP1C, anticorps LSF, anticorps LSF1D, anticorps SEF, anticorps TFCP2C, anticorps CP-2, anticorps CP2, anticorps D230015P20Rik, anticorps LBP-1c, anticorps LBP-1d, anticorps LBP1, anticorps Tcfcp2, anticorps UBP-1, anticorps transcription factor CP2, anticorps transcription factor CP2 L homeolog, anticorps tfcp2, anticorps TFCP2, anticorps tfcp2.L, anticorps Tfcp2

Sujet: LSF (alphaCP2 or LBP-1c) is a transcription factor originally identified by its binding to, and induction of, the SV40 late promoter. LSF displays some similarity to the Elf-1/NTF transcription factors of Drosophila. It is primarily found in its dimeric form in solution, however it is the tetrameric form that recognizes a center-to-center 10 bp repeat. LSF-1D (LBP-1d) is the product of an alternative splicing event, resulting in a deletion of a 51 amino acid segment that corresponds with the DNA-binding region of LSF. LSF-1D is found in the cytoplasm, not in the nucleus, and can interact with LSF to form a heterotetramer that can interfere with LSF DNA binding. In mitogen-stimulated human peripheral T cells, LSF is phosphorylated on amino acid 291, which increases its DNA binding activity. Thus, LSF-mediated gene transcription is regulated by its phosphorylation and/or its interaction with LSF-1D during cell growth. This antibody is routinely tested by western blot analysis.
Synonyms: alphaCP2, LBP-1c

Poids moléculaire: 63 kDa