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GTF2I anticorps (AA 17-123)

GTF2I Reactivité: Humain, Souris, Rat, Chien WB, IF Hôte: Souris Monoclonal 42-TFII unconjugated
N° du produit ABIN968264
  • Antigène Voir toutes GTF2I Anticorps
    GTF2I (General Transcription Factor III (GTF2I))
    Épitope
    • 13
    • 8
    • 8
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 17-123
    Reactivité
    • 64
    • 25
    • 19
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Chien
    Hôte
    • 60
    • 4
    Souris
    Clonalité
    • 61
    • 3
    Monoclonal
    Conjugué
    • 37
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GTF2I est non-conjugé
    Application
    • 51
    • 33
    • 16
    • 14
    • 9
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
     Réactivité croisée
    Chien, Souris, Rat (Rattus)
    Attributs du produit
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogène
    Human BAP-135 aa. 17-123
    Clone
    42-TFII
    Isotype
    IgG1
    Top Product
    Discover our top product GTF2I Anticorps primaire
  • Commentaires

    Related Products: ABIN968535, ABIN967389

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store undiluted at -20°C.
  • Yang, Desiderio: "BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 2, pp. 604-9, (1997) (PubMed).

  • Antigène
    GTF2I (General Transcription Factor III (GTF2I))
    Autre désignation
    TFII-I (GTF2I Produits)
    Synonymes
    anticorps BAP135, anticorps BTKAP1, anticorps DIWS, anticorps GTFII-I, anticorps IB291, anticorps SPIN, anticorps TFII-I, anticorps WBS, anticorps WBSCR6, anticorps Gtf2ird1, anticorps 6030441I21Rik, anticorps BAP-135, anticorps GtfII-I, anticorps Spin, anticorps bap-135, anticorps bap135, anticorps btkap1, anticorps diws, anticorps gtfii-i, anticorps ib291, anticorps spin, anticorps tfii-i, anticorps wbs, anticorps wbscr6, anticorps gtf2i, anticorps gtf2i.L, anticorps general transcription factor IIi, anticorps general transcription factor II I, anticorps general transcription factor IIi S homeolog, anticorps GTF2I, anticorps Gtf2i, anticorps gtf2i, anticorps gtf2i.S
    Sujet
    General transcription factor II-I (GTF2I/TFII-I/SPIN/BAP-135) is a transcription factor that contains six directly repeated 90-residue regions, which possess helix-loop-helix protein-protein interaction motifs. TFII-I can regulate transcription in T-cells through interaction with the initiator elments (Inrs) within the AdML and Vbeta promoters, and associates with HIV-1, TdT, and ribonucleotide reductase R1 Inrs. In addition, TFII-I associates with the E box motif, the CACGTG sequence, and with serum response element sequences. The helix-loop-helix repeats facilitate TFII-I interaction with other transcription factors, such as USF, Myc, Phox 1, MADS box protein serum response factor, and STATs. TFII-I was also identified as Bruton's tyrosine kinase (btk)-associated protein (BAP-135). TFII-I/BAP-135 is tyrosine phosphorylated by btk and after EGF stimulation, and this phosphorylation enhances TFII-I transcriptional activity. The wide expression of TFII-I and the interaction of TFII-I with various Inrs and transcription factors implicates TFII-I in various signaling pathways that regulate gene transcription.
    Synonyms: BAP-135
    Poids moléculaire
    135/140 kDa
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