Smooth Muscle Actin anticorps

N° du produit ABIN968947

Détail du produit anti-Smooth Muscle Actin anticorps

Antigène: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Reactivité: Humain, Rat, Souris, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Smooth Muscle Actin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)

Immunogène: Synthesized peptide of human ACTA2.

Clone: 4A4

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-Smooth Muscle Actin (ABIN968947)

Shimojima, Yamamoto: "ACTA2 is not a major disease-causing gene for moyamoya disease." dans: Journal of human genetics, Vol. 54, Issue 11, pp. 687-8, (2009) (PubMed).

Morisaki, Akutsu, Ogino, Kondo, Yamanaka, Tsutsumi, Yoshimuta, Okajima, Matsuda, Minatoya, Sasaki, Tanaka, Ishibashi-Ueda, Morisaki: "Mutation of ACTA2 gene as an important cause of familial and nonfamilial nonsyndromatic thoracic aortic aneurysm and/or dissection (TAAD)." dans: Human mutation, Vol. 30, Issue 10, pp. 1406-11, (2009) (PubMed).

Détails sur Smooth Muscle Actin

Antigène: Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))

Autre désignation: ACTA2 (ACTA2 Produits)

Synonymes: anticorps AAT6, anticorps ACTSA, anticorps MYMY5, anticorps GAMMA-ACTIN, anticorps ACT, anticorps ACTA3, anticorps ACTE, anticorps ACTL3, anticorps ACTSG, anticorps Act-4, anticorps Act4, anticorps SMGA, anticorps 0610041G09Rik, anticorps Actvs, anticorps SMalphaA, anticorps a-SMA, anticorps alphaSMA, anticorps wu:fb63d03, anticorps ASMA, anticorps SMactin, anticorps a-sma, anticorps aat6, anticorps actsa, anticorps mymy5, anticorps sm-actin, anticorps ACTA2, anticorps actc1, anticorps ACT-4, anticorps asma, anticorps ACTGE, anticorps actin, alpha 2, smooth muscle, aorta, anticorps actin, gamma 2, smooth muscle, enteric, anticorps actin, alpha 2, smooth muscle, aorta L homeolog, anticorps ACTA2, anticorps ACTG2, anticorps Actg2, anticorps Acta2, anticorps acta2, anticorps acta2.L

Sujet:

Description: The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Aliases: AAT6, ACTSA, α-Smooth Muscle Actin

Poids moléculaire: 42 kDa

ID gène: 59

HGNC: 59

Pathways: Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development