ARNTL anticorps

N° du produit ABIN968967

Détail du produit anti-ARNTL anticorps

Antigène: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ARNTL est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Fonction: ARNTL Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human ARNTL expressed in E. Coli.

Clone: 1C5

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-ARNTL (ABIN968967)

Yosifova, Mushiroda, Stoianov, Vazharova, Dimova, Karachanak, Zaharieva, Milanova, Madjirova, Gerdjikov, Tolev, Velkova, Kirov, Owen, ODonovan, Toncheva, Nakamura: "Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population." dans: Journal of affective disorders, Vol. 117, Issue 1-2, pp. 87-97, (2009) (PubMed).

Lee, Lee, Lee, Park, Kang, Chung, Lee, Kim: "Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex." dans: Molecular and cellular biology, Vol. 28, Issue 19, pp. 6056-65, (2008) (PubMed).

Motzkus, Loumi, Cadenas, Vinson, Forssmann, Maronde: "Activation of human period-1 by PKA or CLOCK/BMAL1 is conferred by separate signal transduction pathways." dans: Chronobiology international, Vol. 24, Issue 5, pp. 783-92, (2007) (PubMed).

Détails sur ARNTL

Antigène: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Autre désignation: ARNTL (ARNTL Produits)

Synonymes: anticorps BMAL1, anticorps BMAL1c, anticorps JAP3, anticorps MOP3, anticorps PASD3, anticorps TIC, anticorps bHLHe5, anticorps Bmal1, anticorps ARNTL, anticorps xBmal1, anticorps arntl, anticorps Arnt3, anticorps BMAL1b, anticorps bmal1b', anticorps aryl hydrocarbon receptor nuclear translocator like, anticorps aryl hydrocarbon receptor nuclear translocator-like, anticorps aryl hydrocarbon receptor nuclear translocator like S homeolog, anticorps ARNTL, anticorps Arntl, anticorps arntl.S, anticorps arntl

Sujet:

Description: The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.

Aliases: TIC, JAP3, MOP3, BMAL1, PASD3, BMAL1c, bHLHe5, MGC47515, ARNTL

Poids moléculaire: 68.7kDa

ID gène: 406

HGNC: 406

UniProt: O00327

Pathways: Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, L'effet Warburg