BLK anticorps
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- Antigène Voir toutes BLK Anticorps
- BLK (B Lymphoid Tyrosine Kinase (BLK))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp BLK est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of BLK expressed in E. coli.
- Clone
- 9D10D1
- Isotype
- IgG2a
- Top Product
- Discover our top product BLK Anticorps primaire
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- Indications d'application
- ELISA: 1:10000, IHC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk." dans: The Journal of experimental medicine, Vol. 198, Issue 12, pp. 1863-73, (2003) (PubMed).
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Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk." dans: The Journal of experimental medicine, Vol. 198, Issue 12, pp. 1863-73, (2003) (PubMed).
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- Antigène
- BLK (B Lymphoid Tyrosine Kinase (BLK))
- Autre désignation
- BLK (BLK Produits)
- Synonymes
- anticorps bltk, anticorps si:dkey-33i22.2, anticorps zgc:136231, anticorps MODY11, anticorps BLK proto-oncogene, Src family tyrosine kinase, anticorps B lymphoid kinase, anticorps blk, anticorps BLK, anticorps Blk
- Sujet
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Description: BLK ( B lymphoid tyrosine kinase), with 505-amino acid protein (about 56KDa), belongs to the Src non-receptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.
Aliases: MGC10442
- ID gène
- 640
- HGNC
- 640
- Pathways
- Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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