BLK anticorps
-
- Antigène Voir toutes BLK Anticorps
- BLK (B Lymphoid Tyrosine Kinase (BLK))
-
Reactivité
- Humain
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp BLK est non-conjugé
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Fonction
- BLK Antibody
- Purification
- Ascitic fluid
- Immunogène
- Purified recombinant fragment of BLK expressed in E. Coli.
- Clone
- 9D10B7
- Isotype
- IgG1
- Top Product
- Discover our top product BLK Anticorps primaire
-
-
- Indications d'application
- ELISA: 1/10000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk." dans: The Journal of experimental medicine, Vol. 198, Issue 12, pp. 1863-73, (2003) (PubMed).
: "
-
Mimicry of pre-B cell receptor signaling by activation of the tyrosine kinase Blk." dans: The Journal of experimental medicine, Vol. 198, Issue 12, pp. 1863-73, (2003) (PubMed).
-
- Antigène
- BLK (B Lymphoid Tyrosine Kinase (BLK))
- Autre désignation
- BLK (BLK Produits)
- Synonymes
- anticorps bltk, anticorps si:dkey-33i22.2, anticorps zgc:136231, anticorps MODY11, anticorps BLK proto-oncogene, Src family tyrosine kinase, anticorps B lymphoid kinase, anticorps blk, anticorps BLK, anticorps Blk
- Sujet
-
Description: BLK ( B lymphoid tyrosine kinase), with 505-amino acid protein (about 56KDa), belongs to the Src non-receptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.
Aliases: MGC10442
- ID gène
- 640
- HGNC
- 640
- UniProt
- P51451
- Pathways
- Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
-