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BMI1 anticorps

BMI1 Reactivité: Humain ELISA, IHC, ICC, FACS Hôte: Souris Monoclonal 3E3 unconjugated
N° du produit ABIN968985
  • Antigène Voir toutes BMI1 Anticorps
    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
    Reactivité
    • 103
    • 46
    • 26
    • 11
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 73
    • 28
    • 6
    Souris
    Clonalité
    • 75
    • 32
    Monoclonal
    Conjugué
    • 76
    • 8
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BMI1 est non-conjugé
    Application
    • 84
    • 42
    • 38
    • 18
    • 12
    • 12
    • 11
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Fonction
    BMI1 Antibody
    Purification
    Ascitic fluid
    Immunogène
    Purified recombinant fragment of human BMI1 expressed in E. Coli.
    Clone
    3E3
    Isotype
    IgG1
    Top Product
    Discover our top product BMI1 Anticorps primaire
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Edwards, Witherspoon, Wang, Afrasiabi, Pham, Birnbaumer, Lipkin: "Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer." dans: Cancer research, Vol. 69, Issue 16, pp. 6423-9, (2009) (PubMed).

    Bhattacharya, Nicoloso, Arvizo, Wang, Cortez, Rossi, Calin, Mukherjee: "MiR-15a and MiR-16 control Bmi-1 expression in ovarian cancer." dans: Cancer research, Vol. 69, Issue 23, pp. 9090-5, (2009) (PubMed).

  • Antigène
    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
    Autre désignation
    BMI1 (BMI1 Produits)
    Sujet

    Description: Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

    Aliases: PCGF4, RNF51, MGC12685, FLVI2/BMI1

    Poids moléculaire
    37kDa
    ID gène
    648
    HGNC
    648
    UniProt
    P35226
    Pathways
    Cycle Cellulaire, Autophagy
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