Integrin beta 2 anticorps
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- Antigène Voir toutes Integrin beta 2 (ITGB2) Anticorps
- Integrin beta 2 (ITGB2)
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Reactivité
- Humain, Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Integrin beta 2 est non-conjugé
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Application
- ELISA, Immunocytochemistry (ICC)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of CD18 expressed in E. coli.
- Clone
- 1-00E-13
- Isotype
- IgG2b
- Top Product
- Discover our top product ITGB2 Anticorps primaire
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- Indications d'application
- ELISA: 1:10000, ICC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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The atypical zeta (zeta) isoform of protein kinase C regulates CD11b/CD18 activation in human neutrophils." dans: Microcirculation (New York, N.Y. : 1994), Vol. 15, Issue 6, pp. 555-67, (2008) (PubMed).
: "The context of HLA-DR/CD18 complex in the plasma membrane governs HLA-DR-derived signals in activated monocytes." dans: Molecular immunology, Vol. 45, Issue 3, pp. 709-18, (2007) (PubMed).
: "The cytosolic protein talin induces an intermediate affinity integrin alphaLbeta2." dans: The Journal of biological chemistry, Vol. 282, Issue 33, pp. 24310-9, (2007) (PubMed).
: "
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The atypical zeta (zeta) isoform of protein kinase C regulates CD11b/CD18 activation in human neutrophils." dans: Microcirculation (New York, N.Y. : 1994), Vol. 15, Issue 6, pp. 555-67, (2008) (PubMed).
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- Antigène
- Integrin beta 2 (ITGB2)
- Autre désignation
- CD18 (ITGB2 Produits)
- Synonymes
- anticorps CD18, anticorps LAD, anticorps LCAMB, anticorps LFA-1, anticorps MAC-1, anticorps MF17, anticorps MFI7, anticorps 2E6, anticorps AI528527, anticorps Cd18, anticorps Lfa1, anticorps ITGB2, anticorps itgb2, anticorps itgb2-a, anticorps itgb2-b, anticorps integrin subunit beta 2, anticorps integrin beta 2, anticorps integrin subunit beta 2 S homeolog, anticorps ITGB2, anticorps Itgb2, anticorps itgb2.S
- Sujet
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Description: CD18, also known as ITGB2 (integrin beta chain beta 2). Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. CD18 is expressed by most leucocytes. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.
Aliases: LAD, MF17, LCAMB, LFA-1, ITGB2
- Poids moléculaire
- 85 kDa
- ID gène
- 3689
- HGNC
- 3689
- Pathways
- Signalisation NF-kappaB, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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