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N-Cadherin anticorps

CDH2 Reactivité: Humain WB, IHC, FACS, ELISA, ICC Hôte: Souris Monoclonal 5D5 unconjugated
N° du produit ABIN969038
  • Antigène Voir toutes N-Cadherin (CDH2) Anticorps
    N-Cadherin (CDH2) (Cadherin 2 (CDH2))
    Reactivité
    • 146
    • 93
    • 68
    • 21
    • 16
    • 15
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 92
    • 61
    • 4
    • 4
    • 2
    Souris
    Clonalité
    • 85
    • 78
    Monoclonal
    Conjugué
    • 83
    • 15
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp N-Cadherin est non-conjugé
    Application
    • 114
    • 54
    • 43
    • 41
    • 25
    • 24
    • 17
    • 14
    • 13
    • 12
    • 12
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)
    Fonction
    CDH2 Antibody
    Purification
    Ascitic fluid
    Immunogène
    Purified recombinant fragment of human CDH2 expressed in E. Coli.
    Clone
    5D5
    Isotype
    IgG1
    Top Product
    Discover our top product CDH2 Anticorps primaire
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Wallerand, Cai, Wainberg, Garraway, Lascombe, Nicolle, Thiery, Bittard, Radvanyi, Reiter: "Phospho-Akt pathway activation and inhibition depends on N-cadherin or phospho-EGFR expression in invasive human bladder cancer cell lines." dans: Urologic oncology, Vol. 28, Issue 2, pp. 180-8, (2010) (PubMed).

    Sharma, Henderson: "IQ-domain GTPase-activating protein 1 regulates beta-catenin at membrane ruffles and its role in macropinocytosis of N-cadherin and adenomatous polyposis coli." dans: The Journal of biological chemistry, Vol. 282, Issue 11, pp. 8545-56, (2007) (PubMed).

  • Antigène
    N-Cadherin (CDH2) (Cadherin 2 (CDH2))
    Autre désignation
    CDH2 (CDH2 Produits)
    Synonymes
    anticorps CD325, anticorps CDHN, anticorps CDw325, anticorps NCAD, anticorps N-cadherin, anticorps cadherin-2, anticorps cdhn, anticorps ncad, anticorps cdw325, anticorps CDH2, anticorps Cadherin-2, anticorps Ncad, anticorps glo, anticorps lyr, anticorps pac, anticorps wu:fb47h04, anticorps cadherin 2, anticorps cadherin 2 S homeolog, anticorps cadherin 2, type 1, N-cadherin (neuronal), anticorps CDH2, anticorps cdh2.S, anticorps cdh2, anticorps Cdh2
    Sujet

    Description: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.

    Aliases: CDHN, NCAD, CD325, CDw325, CDH2

    Poids moléculaire
    99.8kDa
    ID gène
    1000
    HGNC
    1000
    UniProt
    P19022
    Pathways
    Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane
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