CRTC3 anticorps

N° du produit ABIN969068

Détail du produit anti-CRTC3 anticorps

Antigène: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CRTC3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Fonction: CRTC3 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human CRTC3 expressed in E. Coli.

Clone: 5G9

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-CRTC3 (ABIN969068)

Nakayama, Miyabe, Okabe, Sakuma, Ijichi, Hasegawa, Nagatsuka, Shimozato, Inagaki: "Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma." dans: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 22, Issue 12, pp. 1575-81, (2009) (PubMed).

Fehr, Röser, Heidorn, Hallas, Löning, Bullerdiek: "A new type of MAML2 fusion in mucoepidermoid carcinoma." dans: Genes, chromosomes & cancer, Vol. 47, Issue 3, pp. 203-6, (2008) (PubMed).

Détails sur CRTC3

Antigène: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Autre désignation: CRTC3 (CRTC3 Produits)

Synonymes: anticorps torc3, anticorps MGC146372, anticorps 2610312F20Rik, anticorps 6332415K15Rik, anticorps AI429792, anticorps BC011210, anticorps TORC3, anticorps RGD1309666, anticorps TORC-3, anticorps CREB regulated transcription coactivator 3, anticorps CREB regulated transcription coactivator 3 L homeolog, anticorps CRTC3, anticorps crtc3, anticorps Crtc3, anticorps crtc3.L

Sujet:

Description: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) .Tissue specificity: Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach.

Aliases: TORC3, FLJ21868, CRTC3

Poids moléculaire: 68kDa

ID gène: 64784

HGNC: 64784

UniProt: Q6UUV7

Pathways: SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2