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CTCF anticorps

CTCF Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 1D11 unconjugated
N° du produit ABIN969071
  • Antigène Voir toutes CTCF Anticorps
    CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
    Reactivité
    • 52
    • 35
    • 32
    • 8
    • 8
    • 7
    • 7
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 45
    • 5
    • 2
    • 1
    • 1
    Souris
    Clonalité
    • 37
    • 17
    Monoclonal
    Conjugué
    • 40
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp CTCF est non-conjugé
    Application
    • 33
    • 10
    • 10
    • 9
    • 9
    • 7
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Fonction
    CTCF Antibody
    Purification
    Ascitic fluid
    Immunogène
    Purified recombinant fragment of human CTCF expressed in E. Coli.
    Clone
    1D11
    Isotype
    IgG1
    Top Product
    Discover our top product CTCF Anticorps primaire
  • Indications d'application
    ELISA: 1/10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Grbesa, Marinkovic, Ivkic, Kruslin, Novak-Kujundzic, Pegan, Bogdanovic, Bedekovic, Gall-Troselj: "Loss of imprinting of IGF2 and H19, loss of heterozygosity of IGF2R and CTCF, and Helicobacter pylori infection in laryngeal squamous cell carcinoma." dans: Journal of molecular medicine (Berlin, Germany), Vol. 86, Issue 9, pp. 1057-66, (2008) (PubMed).

    Majumder, Gomez, Chadwick, Boss: "The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions." dans: The Journal of experimental medicine, Vol. 205, Issue 4, pp. 785-98, (2008) (PubMed).

    Stedman, Kang, Lin, Kissil, Bartolomei, Lieberman: "Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators." dans: The EMBO journal, Vol. 27, Issue 4, pp. 654-66, (2008) (PubMed).

  • Antigène
    CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
    Autre désignation
    CTCF (CTCF Produits)
    Synonymes
    anticorps im:7152666, anticorps CTCF, anticorps xctcf, anticorps AW108038, anticorps CCCTC-binding factor, anticorps CCCTC-binding factor (zinc finger protein), anticorps CTCF, anticorps ctcf, anticorps Ctcf
    Sujet

    Description: This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors.Tissue specificity: Ubiquitous. Absent in primary spermatocytes.

    Aliases: CTCF

    Poids moléculaire
    83kDa
    ID gène
    10664
    HGNC
    10664
    UniProt
    P49711
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