EPH Receptor B3 anticorps (AA 39-212)

N° du produit ABIN969106

Détail du produit anti-EPH Receptor B3 anticorps

Antigène: EPH Receptor B3 (EPHB3)

Épitope: AA 39-212

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EPH Receptor B3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Fonction: EphB3 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of EphB3 (aa39-212) expressed in E. Coli.

Clone: 4A122D1

Isotype: IgG2a

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-EPH Receptor B3 (ABIN969106)

Trivier, Ganesan: "RYK, a catalytically inactive receptor tyrosine kinase, associates with EphB2 and EphB3 but does not interact with AF-6." dans: The Journal of biological chemistry, Vol. 277, Issue 25, pp. 23037-43, (2002) (PubMed).

Bergemann, Zhang, Chiang, Brambilla, Klein, Flanagan: "Ephrin-B3, a ligand for the receptor EphB3, expressed at the midline of the developing neural tube." dans: Oncogene, Vol. 16, Issue 4, pp. 471-80, (1998) (PubMed).

Hock, Böhme, Karn, Yamamoto, Kaibuchi, Holtrich, Holland, Pawson, Rübsamen-Waigmann, Strebhardt: "PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 17, pp. 9779-84, (1998) (PubMed).

Détails sur EPH Receptor B3

Antigène: EPH Receptor B3 (EPHB3)

Autre désignation: EphB3 (EPHB3 Produits)

Sujet:

Description: EphB3: EPH receptor B3. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.

Aliases: ETK2, HEK2, TYRO6

ID gène: 2049

HGNC: 2049

UniProt: P54753

Pathways: Signalisation RTK