Estrogen Receptor alpha anticorps
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- Antigène Voir toutes Estrogen Receptor alpha (ESR1) Anticorps
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Estrogen Receptor alpha est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human ESR1 expressed in E. coli.
- Clone
- 6B6
- Isotype
- IgG1
- Top Product
- Discover our top product ESR1 Anticorps primaire
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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Binding of the ERalpha nuclear receptor to DNA is coupled to proton uptake." dans: Biochemistry, Vol. 49, Issue 29, pp. 5978-88, (2010) (PubMed).
: "Genotypes and haplotypes of the estrogen receptor genes, but not the retinoblastoma-interacting zinc finger protein 1 gene, are associated with osteoporosis." dans: Calcified tissue international, Vol. 87, Issue 1, pp. 25-35, (2010) (PubMed).
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Binding of the ERalpha nuclear receptor to DNA is coupled to proton uptake." dans: Biochemistry, Vol. 49, Issue 29, pp. 5978-88, (2010) (PubMed).
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- Antigène
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
- Autre désignation
- ESR1 (ESR1 Produits)
- Synonymes
- anticorps LOC398734, anticorps AA420328, anticorps AU041214, anticorps ER-alpha, anticorps ER[a], anticorps ERa, anticorps ERalpha, anticorps ESR, anticorps Estr, anticorps Estra, anticorps Nr3a1, anticorps NR3A1, anticorps eralpha, anticorps zfER[a], anticorps ER, anticorps ESRA, anticorps ESTRR, anticorps Era, anticorps akap12, anticorps cb27, anticorps esr1, anticorps fb72g12, anticorps id:ibd1202, anticorps sb:cb27, anticorps si:ch73-192g21.1, anticorps wu:fb72g12, anticorps wu:fc21c03, anticorps Esr, anticorps RNESTROR, anticorps ERALPHA, anticorps er, anticorps esr, anticorps nr3a1, anticorps XER, anticorps era, anticorps esra, anticorps ERbeta, anticorps xesr-1, anticorps xlERalpha1, anticorps xlERalpha2, anticorps ESR1, anticorps estrogen receptor 1 L homeolog, anticorps estrogen receptor 1 (alpha), anticorps estrogen receptor 1, anticorps A kinase (PRKA) anchor protein 12b, anticorps esr1.L, anticorps Esr1, anticorps ESR1, anticorps esr1, anticorps akap12b
- Sujet
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Description: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.
Aliases: ER, ESR, Era, ESRA, NR3A1, DKFZp686N23123, ESR1
- Poids moléculaire
- 66 kDa
- ID gène
- 2099
- HGNC
- 2099
- Pathways
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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